Po-Ru Loh : rechercher sur Z-Library

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1

Genetic Evidence for Recent Population Mixture in India

Moorjani, Priya, Thangaraj, Kumarasamy, Patterson, Nick, Lipson, Mark, Loh, Po-Ru, Govindaraj, Periyasamy, Berger, Bonnie, Reich, David, Singh, Lalji

Journal:

The American Journal of Human Genetics

Année:

2013

Langue:

english

Fichier:

PDF, 884 KB

english, 2013

2

Stepping to Infinity Along Gaussian Primes

Journal:

American Mathematical Monthly

Année:

2007

Langue:

english

Fichier:

PDF, 1010 KB

english, 2007

3

Fast, sensitive and accurate integration of single-cell data with Harmony

Korsunsky, Ilya, Millard, Nghia, Fan, Jean, Slowikowski, Kamil, Zhang, Fan, Wei, Kevin, Baglaenko, Yuriy, Brenner, Michael, Loh, Po-ru, Raychaudhuri, Soumya

Journal:

Année:

2019

Fichier:

PDF, 5.09 MB

2019

4

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Bulik-Sullivan, Brendan K, Loh, Po-Ru, Finucane, Hilary K, Ripke, Stephan, Yang, Jian, Patterson, Nick, Daly, Mark J, Price, Alkes L, Neale, Benjamin M

Journal:

Nature Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 593 KB

english, 2015

5

p-ADIC AND COMBINATORIAL PROPERTIES OF MODULAR FORM COEFFICIENTS

LOH, PO-RU, RHOADES, ROBERT C.

Journal:

International Journal of Number Theory

Année:

2006

Langue:

english

Fichier:

PDF, 296 KB

english, 2006

6

An atlas of genetic correlations across human diseases and traits

Bulik-Sullivan, Brendan, Finucane, Hilary K, Anttila, Verneri, Gusev, Alexander, Day, Felix R, Loh, Po-Ru, Duncan, Laramie, Perry, John R B, Patterson, Nick, Robinson, Elise B, Daly, Mark J, Price, Al

Journal:

Nature Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 670 KB

english, 2015

7

Stepping to Infinity Along Gaussian Primes

Journal:

American Mathematical Monthly

Année:

2007

Langue:

english

Fichier:

PDF, 382 KB

english, 2007

8

Assessing statistical significance in causal graphs

Leonid Chindelevitch, Po-Ru Loh, Ahmed Enayetallah, Bonnie Berger, Daniel Ziemek

Journal:

BMC Bioinformatics

Année:

2012

Langue:

english

Fichier:

PDF, 402 KB

english, 2012

9

Prize-based contests can provide solutions to computational biology problems

Lakhani, Karim R, Boudreau, Kevin J, Loh, Po-Ru, Backstrom, Lars, Baldwin, Carliss, Lonstein, Eric, Lydon, Mike, MacCormack, Alan, Arnaout, Ramy A, Guinan, Eva C

Journal:

Nature Biotechnology

Année:

2013

Langue:

english

Fichier:

PDF, 515 KB

english, 2013

10

Reconstructing Austronesian population history in Island Southeast Asia

Lipson, Mark, Loh, Po-Ru, Patterson, Nick, Moorjani, Priya, Ko, Ying-Chin, Stoneking, Mark, Berger, Bonnie, Reich, David

Journal:

Nature Communications

Année:

2014

Langue:

english

Fichier:

PDF, 453 KB

english, 2014

11

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, Bjarni J., Yang, Jian, Finucane, Hilary K., Gusev, Alexander, Lindström, Sara, Ripke, Stephan, Genovese, Giulio, Loh, Po-Ru, Bhatia, Gaurav, Do, Ron, Hayeck, Tristan, Won, Hong-Hee, Kath

Journal:

The American Journal of Human Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 492 KB

english, 2015

12

Physical and neurobehavioral determinants of reproductive onset and success

Day, Felix R, Helgason, Hannes, Chasman, Daniel I, Rose, Lynda M, Loh, Po-Ru, Scott, Robert A, Helgason, Agnar, Kong, Augustine, Masson, Gisli, Magnusson, Olafur Th, Gudbjartsson, Daniel, Thorsteinsdo

Journal:

Nature Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2016

13

Reference-based phasing using the Haplotype Reference Consortium panel

Loh, Po-Ru, Danecek, Petr, Palamara, Pier Francesco, Fuchsberger, Christian, A Reshef, Yakir, K Finucane, Hilary, Schoenherr, Sebastian, Forer, Lukas, McCarthy, Shane, Abecasis, Goncalo R, Durbin, Ric

Journal:

Nature Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 556 KB

english, 2016

14

Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits

Hormozdiari, Farhad, Gazal, Steven, van de Geijn, Bryce, Finucane, Hilary K., Ju, Chelsea J.-T., Loh, Po-Ru, Schoech, Armin, Reshef, Yakir, Liu, Xuanyao, O’Connor, Luke, Gusev, Alexander, Eskin, Eleaz

Journal:

Nature Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 3.06 MB

english, 2018

15

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

Reshef, Yakir A., Finucane, Hilary K., Kelley, David R., Gusev, Alexander, Kotliar, Dylan, Ulirsch, Jacob C., Hormozdiari, Farhad, Nasser, Joseph, O’Connor, Luke, van de Geijn, Bryce, Loh, Po-Ru, Gros

Journal:

Nature Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 7.44 MB

english, 2018

16

Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes

Chung, Wonil, Chen, Jun, Turman, Constance, Lindstrom, Sara, Zhu, Zhaozhong, Loh, Po-Ru, Kraft, Peter, Liang, Liming

Journal:

Nature Communications

Année:

2019

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2019

17

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection

Schoech, Armin P., Jordan, Daniel M., Loh, Po-Ru, Gazal, Steven, O’Connor, Luke J., Balick, Daniel J., Palamara, Pier F., Finucane, Hilary K., Sunyaev, Shamil R., Price, Alkes L.

Journal:

Nature Communications

Année:

2019

Langue:

english

Fichier:

PDF, 807 KB

english, 2019

18

Compressive genomics

Loh, Po-Ru, Baym, Michael, Berger, Bonnie

Journal:

Nature Biotechnology

Année:

2012

Langue:

english

Fichier:

PDF, 327 KB

english, 2012

19

Network topology and parameter estimation: from experimental design methods to gene regulatory network kinetics using a community based approach

Meyer, Pablo, Cokelaer, Thomas, Chandran, Deepak, Kim, Kyung, Loh, Po-Ru, Tucker, George, Lipson, Mark, Berger, Bonnie, Kreutz, Clemens, Raue, Andreas, Steiert, Bernhard, Timmer, Jens, Bilal, Erhan, D

Journal:

BMC Systems Biology

Année:

2014

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2014

20

Fundamental relation between phase and group velocity, and application to the failure of perfectly matched layers in backward-wave structures

Loh, Po-Ru, Oskooi, Ardavan F., Ibanescu, Mihai, Skorobogatiy, Maksim, Johnson, Steven G.

Journal:

Physical Review E

Année:

2009

Langue:

english

Fichier:

PDF, 232 KB

english, 2009

21

Efficient Bayesian mixed-model analysis increases association power in large cohorts

Loh, Po-Ru, Tucker, George, Bulik-Sullivan, Brendan K, Vilhjálmsson, Bjarni J, Finucane, Hilary K, Salem, Rany M, Chasman, Daniel I, Ridker, Paul M, Neale, Benjamin M, Berger, Bonnie, Patterson, Nick,

Journal:

Nature Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 774 KB

english, 2015

22

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

Hayeck, Tristan J., Zaitlen, Noah A., Loh, Po-Ru, Vilhjalmsson, Bjarni, Pollack, Samuela, Gusev, Alexander, Yang, Jian, Chen, Guo-Bo, Goddard, Michael E., Visscher, Peter M., Patterson, Nick, Price, A

Journal:

The American Journal of Human Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 204 KB

english, 2015

23

Partitioning heritability by functional annotation using genome-wide association summary statistics

Finucane, Hilary K, Bulik-Sullivan, Brendan, Gusev, Alexander, Trynka, Gosia, Reshef, Yakir, Loh, Po-Ru, Anttila, Verneri, Xu, Han, Zang, Chongzhi, Farh, Kyle, Ripke, Stephan, Day, Felix R, Purcell, S

Journal:

Nature Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 921 KB

english, 2015

24

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

Loh, Po-Ru, Bhatia, Gaurav, Gusev, Alexander, Finucane, Hilary K, Bulik-Sullivan, Brendan K, Pollack, Samuela J, de Candia, Teresa R, Lee, Sang Hong, Wray, Naomi R, Kendler, Kenneth S, O'Donovan, Mich

Journal:

Nature Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 1018 KB

english, 2015

25

Two-Variance-Component Model Improves Genetic Prediction in Family Datasets

Tucker, George, Loh, Po-Ru, MacLeod, Iona M., Hayes, Ben J., Goddard, Michael E., Berger, Bonnie, Price, Alkes L.

Journal:

The American Journal of Human Genetics

Année:

2015

Langue:

english

Fichier:

PDF, 327 KB

english, 2015

26

A Robust Example of Collider Bias in a Genetic Association Study

Day, Felix R., Loh, Po-Ru, Scott, Robert A., Ong, Ken K., Perry, John R.B.

Journal:

The American Journal of Human Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 376 KB

english, 2016

27

Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia

Galinsky, Kevin J., Bhatia, Gaurav, Loh, Po-Ru, Georgiev, Stoyan, Mukherjee, Sayan, Patterson, Nick J., Price, Alkes L.

Journal:

The American Journal of Human Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2016

28

A sampling framework for incorporating quantitative mass spectrometry data in protein interaction analysis

Tucker, George, Loh, Po-Ru, Berger, Bonnie

Journal:

BMC Bioinformatics

Année:

2013

Langue:

english

Fichier:

PDF, 787 KB

english, 2013

29

Fast and accurate long-range phasing in a UK Biobank cohort

Loh, Po-Ru, Palamara, Pier Francesco, Price, Alkes L

Journal:

Nature Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 532 KB

english, 2016

30

Population Structure of UK Biobank and Ancient Eurasians Reveals Adaptation at Genes Influencing Blood Pressure

Galinsky, Kevin J., Loh, Po-Ru, Mallick, Swapan, Patterson, Nick J., Price, Alkes L.

Journal:

The American Journal of Human Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2016

31

Response to Shen et al.

Galinsky, Kevin J., Bhatia, Gaurav, Loh, Po-Ru, Georgiev, Stoyan, Mukherjee, Sayan, Patterson, Nick J., Price, Alkes L.

Journal:

The American Journal of Human Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 325 KB

english, 2016

32

Mixed Model Association with Family-Biased Case-Control Ascertainment

Hayeck, Tristan J., Loh, Po-Ru, Pollack, Samuela, Gusev, Alexander, Patterson, Nick, Zaitlen, Noah A., Price, Alkes L.

Journal:

The American Journal of Human Genetics

Année:

2017

Langue:

english

Fichier:

PDF, 175 KB

english, 2017

33

Stepwise Distributed Open Innovation Contests for Software Development - Acceleration of Genome-Wide Association Analysis

Hill, Andrew, Loh, Po-Ru, Bharadwaj, Ragu B., Pons, Pascal, Shang, Jingbo, Guinan, Eva, Lakhani, Karim, Kilty, Iain, Jelinsky, Scott A.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2017

34

Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

Gazal, Steven, Finucane, Hilary K, Furlotte, Nicholas A, Loh, Po-Ru, Palamara, Pier Francesco, Liu, Xuanyao, Schoech, Armin, Bulik-Sullivan, Brendan, Neale, Benjamin M, Gusev, Alexander, Price, Alkes

Journal:

Nature Genetics

Année:

2017

Langue:

english

Fichier:

PDF, 741 KB

english, 2017

35

Multiethnic polygenic risk scores improve risk prediction in diverse populations

Márquez-Luna, Carla, Loh, Po-Ru, Price, Alkes L.

Journal:

Genetic Epidemiology

Année:

2017

Langue:

english

Fichier:

PDF, 513 KB

english, 2017

36

Heritability of Atrial FibrillationCLINICAL PERSPECTIVE

Weng, Lu-Chen, Choi, Seung Hoan, Klarin, Derek, Smith, J. Gustav, Loh, Po-Ru, Chaffin, Mark, Roselli, Carolina, Hulme, Olivia L., Lunetta, Kathryn L., Dupuis, Josée, Benjamin, Emelia J., Newton-Cheh,

Journal:

Circulation Cardiovascular Genetics

Année:

2017

Langue:

english

Fichier:

PDF, 843 KB

english, 2017

37

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases

Zhu, Zhaozhong, Lee, Phil H., Chaffin, Mark D., Chung, Wonil, Loh, Po-Ru, Lu, Quan, Christiani, David C., Liang, Liming

Journal:

Nature Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2018

38

Mixed-model association for biobank-scale datasets

Loh, Po-Ru, Kichaev, Gleb, Gazal, Steven, Schoech, Armin P., Price, Alkes L.

Journal:

Nature Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2018

39

Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

Lipson, Mark, Loh, Po-Ru, Sankararaman, Sriram, Patterson, Nick, Berger, Bonnie, Reich, David, Coop, Graham

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.43 MB

english, 2015

40

Phenotype Prediction Using Regularized Regression on Genetic Data in the DREAM5 Systems Genetics B Challenge

Loh, Po-Ru, Tucker, George, Berger, Bonnie, Isalan, Mark

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2011

41

Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations

Loh, Po-Ru, Genovese, Giulio, Handsaker, Robert E., Finucane, Hilary K., Reshef, Yakir A., Palamara, Pier Francesco, Birmann, Brenda M., Talkowski, Michael E., Bakhoum, Samuel F., McCarroll, Steven A.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 4.60 MB

english, 2018

42

Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations

Gazal, Steven, Loh, Po-Ru, Finucane, Hilary K., Ganna, Andrea, Schoech, Armin, Sunyaev, Shamil, Price, Alkes L.

Journal:

Nature Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 2.83 MB

english, 2018

43

Author Correction: A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases

Zhu, Zhaozhong, Lee, Phil H., Chaffin, Mark D., Chung, Wonil, Loh, Po-Ru, Lu, Quan, Christiani, David C., Liang, Liming

Journal:

Nature Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 481 KB

english, 2018

44

Estimating cross-population genetic correlations of causal effect sizes

Galinsky, Kevin J., Reshef, Yakir A., Finucane, Hilary K., Loh, Po-Ru, Zaitlen, Noah, Patterson, Nick J., Brown, Brielin C., Price, Alkes L.

Journal:

Genetic Epidemiology

Année:

2018

Langue:

english

Fichier:

PDF, 488 KB

english, 2018

45

Leveraging Polygenic Functional Enrichment to Improve GWAS Power

Kichaev, Gleb, Bhatia, Gaurav, Loh, Po-Ru, Gazal, Steven, Burch, Kathryn, Freund, Malika K., Schoech, Armin, Pasaniuc, Bogdan, Price, Alkes L.

Journal:

The American Journal of Human Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 609 KB

english, 2018

46

Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes

Chung, Wonil, Chen, Jun, Turman, Constance, Lindstrom, Sara, Zhu, Zhaozhong, Loh, Po-Ru, Kraft, Peter, Liang, Liming

Journal:

Nature Communications

Année:

2019

Fichier:

PDF, 1.25 MB

2019

47

Genes with High Network Connectivity Are Enriched for Disease Heritability

Kim, Samuel S., Dai, Chengzhen, Hormozdiari, Farhad, van de Geijn, Bryce, Gazal, Steven, Park, Yongjin, O’Connor, Luke, Amariuta, Tiffany, Loh, Po-Ru, Finucane, Hilary, Raychaudhuri, Soumya, Price, Al

Journal:

The American Journal of Human Genetics

Année:

2019

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2019

48

Author Correction: Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

Gazal, Steven, Finucane, Hilary K., Furlotte, Nicholas A., Loh, Po-Ru, Palamara, Pier Francesco, Liu, Xuanyao, Schoech, Armin, Bulik-Sullivan, Brendan, Neale, Benjamin M., Gusev, Alexander, Price, Alk

Journal:

Nature Genetics

Année:

2019

Fichier:

PDF, 477 KB

2019

49

GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation

Terao, Chikashi, Momozawa, Yukihide, Ishigaki, Kazuyoshi, Kawakami, Eiryo, Akiyama, Masato, Loh, Po-Ru, Genovese, Giulio, Sugishita, Hiroki, Ohta, Tazro, Hirata, Makoto, Perry, John R. B., Matsuda, Ko

Journal:

Nature Communications

Année:

2019

Fichier:

PDF, 1024 KB

2019

50

Liability threshold modeling of caseâcontrol status and family history of disease increases association power

Hujoel, Margaux L. A., Gazal, Steven, Loh, Po-Ru, Patterson, Nick, Price, Alkes L.

Journal:

Nature Genetics

Année:

2020

Fichier:

PDF, 3.62 MB

2020